Carbon is developing a suite of next generation viral vectors constructed from viruses that have naturally evolved over millions of years. Our CBN Vector Library was designed by our team of preeminent experts in in Virology and Molecular Biology and is comprised of novel delivery vehicles that differentiate from current viral vectors with increased cargo packaging size, unique tropism and immunological profiles that can enable durable treatment strategies. Our vectors can be manufactured using industrial scale viral production platforms and can be used to deliver a wide-range of therapeutic modalities.

Our first program, CGT-001, utilizes the CBN-1000 vector which has demonstrated highly specific lung airway tropism, significantly increased packaging capacity and the ability to be readministered in animal models. CGT-001 is designed to enable airway delivery of the full length CFTR gene for Cystic Fibrosis, an approach that has been previously unachievable with current generation viral vectors.